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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1888303Erstellt: 27. Oktober 2026

Ornoprostil → 7-{(1R,2R,3R)-3-hydroxy-2-[(1E,3S,5S)-3-hydroxy-5-methyl-1-nonenyl]-5-oxocyclopentyl}-6-oxoheptanoic acid

https://huagongshe.com/reaction/1888303

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktOrnoprostilHCID 5282205—
Eduktethyl 2-[(2-{(1R,2R)-2-[(1E,3S,5S)-3-hydroxy-5-methyl-1-nonenyl]-5-oxocyclopentyl}ethyl)thio]-1,3-thiazole-4-carboxylateHCID 66858273—
Produkt7-{(1R,2R,3R)-3-hydroxy-2-[(1E,3S,5S)-3-hydroxy-5-methyl-1-nonenyl]-5-oxocyclopentyl}-6-oxoheptanoic acidHCID 10927388—

Reaktionsschritte

By the same procedure as the reaction of Example 30 using methyl 7-{(1R,2R,3R)-3-hydroxy-2-[(1E,3S,5S)-3-hydroxy-5-methyl-1-nonenyl]-5-oxocyclopentyl}-6-oxoheptanoate (Reg No.70667-26-4) instead of the compound 29, the title compound having the following physical data was obtained.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08501793B2
Quelldatensatzuspto-grants-2013_08
ORD IDord-0e96babb74274fc5b0b6d8f4613c210f
Quellennotizuspto-grants-2013_08