3-Oxocyclopentanecarboxylic acid → HCID 178441291, Verbindung

HRID 1888651

Reaktionsgleichung

Reaktionsgleichung von HRID 1888651
[C:1]([N:5]1[CH:9]=[C:8]([CH2:10][CH2:11][CH2:12][CH3:13])[C:7](=[NH:14])[S:6]1)([CH3:4])([CH3:3])[CH3:2].[O:15]=[C:16]1[CH2:20][CH2:19][CH:18]([C:21](O)=[O:22])[CH2:17]1>>[CH2:10]([C:8]1=[CH:9][N:5]([C:1]([CH3:4])([CH3:3])[CH3:2])[S:6]/[C:7]/1=[N:14]\[C:21]([CH:18]1[CH2:19][CH2:20][C:16](=[O:15])[CH2:17]1)=[O:22])[CH2:11][CH2:12][CH3:13]

Komponenten

3

Edukt 2

HCID 2277983-Oxocyclopentanecarboxylic acidHCID 668672282-tert-Butyl-4-butylisothiazol-5(2H)-imine

Produkt 1

HCID 178441291HCID 178441291, Verbindung

Versuchsvorschrift

The product from Example 92B and 3-oxocyclopentanecarboxylic acid (Aldrich) were processed using the method described in Example 92C to afford the title compound. 1H NMR (DMSO-d6) δ ppm 0.91 (t, J=7.5 Hz, 3H), 1.25-1.36 (m, 2H), 1.57 (s, 9H), 1.55-1.84 (m, 2H), 1.98-2.06 (m, 1H), 2.13-2.28 (m, 3H), 2.39-2.42 (m, 2H), 2.61-2.66 (m, 2H), 3.27-3.34 (m, 1H), 8.55 (s, 1H). MS (ESI+) m/z 323 (M+H)+. Anal. calcd. for C17H26N2O2S: C, 63.32; H, 8.13; N, 8.69. Found: C, 63.19; H, 8.07; N, 8.66.

Quellen und Nachweise

ORD-Eintrag
ord-62cb556fd62548d9841d41eb86dc1836
Quelldatensatz
uspto-grants-2013_08
Patentnummer
US08501794B2

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