Hydrochloric Acid → 5-Methylthiazole-4-carbohydrazide
Reaktionsgleichung
[CH3:1][C:2]1[S:6][CH:5]=[N:4][C:3]=1[C:7]([NH:9][NH:10]C(OC(C)(C)C)=O)=[O:8].Cl>>[CH3:1][C:2]1[S:6][CH:5]=[N:4][C:3]=1[C:7]([NH:9][NH2:10])=[O:8]Komponenten
3
Versuchsvorschrift
A mixture of 1,1-dimethylethyl 2-[(5-methyl-1,3-thiazol-4-yl)carbonyl]hydrazinecarboxylate (544 mg, 2.114 mmol) in HCl (2643 μl, 10.57 mmol) (4M in 1,4-dioxane) was stirred at room temperature under an atmosphere of argon for 17 hours (overnight). After this time, the reaction mixture was concentrated under reduced pressure to give an off-white coloured solid of desired material in 162 mg.
Aufarbeitung
- concentrationAfter this time, the reaction mixture was concentrated under reduced pressure
- customto give an off-white coloured solid of desired material in 162 mg
Quellen und Nachweise
- ORD-Eintrag
- ord-e2023f0885fb4087886e93048a792ca3
- Quelldatensatz
- uspto-grants-2013_08
- Patentnummer
- US08501946B2
Notizen zur Reaktion
Wird geladen…