(1H-pyrrolo[2,3-b]pyridin-3-yl)methanamine → Thiazolo[4,5-c]pyridine-2-methanamine

HRID 1890556Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1890556
[S:1]1[C:9]2[CH:8]=[CH:7][N:6]=[CH:5][C:4]=2[N:3]=[C:2]1[CH2:10]O.[NH:12]1C2=NC=CC=C2C(CN)=C1>>[S:1]1[C:9]2[CH:8]=[CH:7][N:6]=[CH:5][C:4]=2[N:3]=[C:2]1[CH2:10][NH2:12]

Komponenten

3

Edukt 2

HCID 17959419(1H-pyrrolo[2,3-b]pyridin-3-yl)methanamineHCID 55296405Thiazolo[4,5-c]pyridin-2-ylmethanol

Produkt 1

HCID 65441030Thiazolo[4,5-c]pyridine-2-methanamine

Versuchsvorschrift

Intermediate R was prepared from thiazolo[4,5-c]pyridin-2-ylmethanol (R-4) following similar procedures for synthesizing intermediate A from A-3, as described above. MS (m/z): 165 (M)+.

Quellen und Nachweise

ORD-Eintrag
ord-3a2efe88f1f244b8afaaf00641fe80e6
Quelldatensatz
uspto-grants-2013_08
Patentnummer
US08507487B2

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