Ethyl isocyanate → HCID 60969782, Verbindung

HRID 1892812Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1892812
[NH2:1][C:2]1[CH:3]=[C:4]([S:9]([NH2:12])(=[O:11])=[O:10])[CH:5]=[CH:6][C:7]=1[Cl:8].[CH2:13]([N:15]=[C:16]=[O:17])[CH3:14]>O1CCCC1>[Cl:8][C:7]1[CH:6]=[CH:5][C:4]([S:9]([NH2:12])(=[O:11])=[O:10])=[CH:3][C:2]=1[NH:1][C:16]([NH:15][CH2:13][CH3:14])=[O:17]

Komponenten

4

Edukt 2

HCID 8022Ethyl isocyanateHCID 957943-Amino-4-chlorobenzenesulphonamide

Produkt 1

HCID 60969782HCID 60969782, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8028TetrahydrofuranLösungsmittel

Versuchsvorschrift

To 3-amino-4-chlorobenzenesulfonamide (420 mg) in tetrahydrofuran (2 ml) solution, ethylisocyanate (180 μl) was added and the mixture was stirred under heating and reflux for 15 hours. The reaction solution was concentrated, then the residue was recrystallized from chloroform/methanol to obtain the title compound as a crude product (550 mg).

Aufarbeitung

  1. temperatureunder heating
  2. temperaturereflux for 15 hours
  3. concentrationThe reaction solution was concentrated
  4. customthe residue was recrystallized from chloroform/methanol

Quellen und Nachweise

ORD-Eintrag
ord-00ae80a5dfa4438ea8b5277e1b3f25ac
Quelldatensatz
uspto-grants-2013_08
Patentnummer
US08507714B2

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