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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1892838Erstellt: 25. Oktober 2026

methyl 2-chloro-5-{[(6E)-6-(5-chloro-2-methoxybenzylidene)-3,7-dioxo-1,4-diazepan-1-yl]sulfonyl}benzoate → Methyl 4-[(6-benzyl-3,7-dioxo-1,4-diazepan-1-yl)sulfonyl]benzoate

https://huagongshe.com/reaction/1892838

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Eduktmethyl 2-chloro-5-{[(6E)-6-(5-chloro-2-methoxybenzylidene)-3,7-dioxo-1,4-diazepan-1-yl]sulfonyl}benzoateHCID 57670914—
Edukt3-[(6-Benzyl-3,7-dioxo-1,4-diazepan-1-yl)sulfonyl]benzoic acidHCID 57671085—
Edukt4-(Tert-butoxycarbonyl)benzenesulfonamideHCID 59733636—
EduktTert-butyl 3-sulfamoylbenzoateHCID 59733695—
Edukt4-[(6-Benzyl-3,7-dioxo-1,4-diazepan-1-yl)sulfonyl]benzoic acidHCID 66934750—
ProduktMethyl 4-[(6-benzyl-3,7-dioxo-1,4-diazepan-1-yl)sulfonyl]benzoateHCID 57670935—

Reaktionsschritte

4-[(6-benzyl-3,7-dioxo-1,4-diazepan-1-yl)sulfonyl]benzoic acid, synthesized by using 4-(tert-butoxycarbonyl)benzenesulfonamide instead of the starting material compound of Example 198, that is, 3-(tert-butoxycarbonyl)benzenesulfonamide for the similar procedure as in Example 198, was used instead of the starting material of Example 208, that is, the compound 196, for the similar procedure as with Example 208 to obtain the title compound.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08507714B2
Quelldatensatzuspto-grants-2013_08
ORD IDord-9a53d7dc76644fdba2b200107e769985
Quellennotizuspto-grants-2013_08