4-Phenylcyclohexanone → HCID 49763342, Verbindung
Reaktionsgleichung
[C:1]1([CH:7]2[CH2:12][CH2:11][C:10](=O)[CH2:9][CH2:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH:14]1[CH2:17][CH:16]([NH:18][C:19]([CH2:21][NH:22][C:23](=[O:38])[C:24]2[CH:29]=[C:28]([C:30]([F:33])([F:32])[F:31])[CH:27]=[C:26]([C:34]([F:37])([F:36])[F:35])[CH:25]=2)=[O:20])[CH2:15]1>>[C:1]1([CH:7]2[CH2:12][CH2:11][CH:10]([N:14]3[CH2:17][CH:16]([NH:18][C:19]([CH2:21][NH:22][C:23](=[O:38])[C:24]4[CH:29]=[C:28]([C:30]([F:33])([F:32])[F:31])[CH:27]=[C:26]([C:34]([F:35])([F:37])[F:36])[CH:25]=4)=[O:20])[CH2:15]3)[CH2:9][CH2:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1Komponenten
3
Versuchsvorschrift
The title compound was prepared as a white solid by reductive amination of 4-phenyl-cyclohexanone (Aldrich) and N-(azetidin-3-ylcarbamoylmethyl)-3,5-bistrifluoromethyl-benzamide (as prepared in the previous step) using the procedure described in Step C of Example 4.
Aufarbeitung
- customas prepared in the previous step)
Quellen und Nachweise
- ORD-Eintrag
- ord-4bbe7791182442608816c26037fb2746
- Quelldatensatz
- uspto-grants-2013_08