Ethyl bromopyruvate → HCID 52903990, Verbindung
Reaktionsgleichung
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([NH:7][C:8]([NH2:10])=[S:9])[CH:2]=1.[CH2:11]([O:13][C:14](=[O:19])[C:15](=O)[CH2:16]Br)[CH3:12]>CO>[CH2:11]([O:13][C:14]([C:15]1[N:10]=[C:8]([NH:7][C:3]2[CH:2]=[N:1][CH:6]=[CH:5][CH:4]=2)[S:9][CH:16]=1)=[O:19])[CH3:12]Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
2-(Pyridin-3-ylamino)-thiazole-4-carboxylic acid ethyl ester (200 mg) was prepared according to General Procedure B using pyridin-3-yl-thiourea (154 mg) and 3-bromo-2-oxo-propionic acid ethyl ester (200 mg) in methanol (2 mL). The crude product was used in subsequent steps without further purification.
Aufarbeitung
- customThe crude product was used in subsequent steps without further purification
Quellen und Nachweise
- ORD-Eintrag
- ord-f22bc225b9594e609f525249a21d1b39
- Quelldatensatz
- uspto-grants-2013_08
- Patentnummer
- US08513430B2
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