Tetrahydrofuran → 2-(3-Pyridinylamino)-4-thiazolecarboxylic acid

HRID 1895391Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1895391
C([O:3][C:4]([C:6]1[N:7]=[C:8]([NH:11][C:12]2[CH:13]=[N:14][CH:15]=[CH:16][CH:17]=2)[S:9][CH:10]=1)=[O:5])C.O1CCCC1.[OH-].[Na+]>CO>[N:14]1[CH:15]=[CH:16][CH:17]=[C:12]([NH:11][C:8]2[S:9][CH:10]=[C:6]([C:4]([OH:5])=[O:3])[N:7]=2)[CH:13]=1

Komponenten

5

Edukt 3

HCID 8028TetrahydrofuranHCID 14798Sodium HydroxideHCID 52903990HCID 52903990, Verbindung

Produkt 1

HCID 529035842-(3-Pyridinylamino)-4-thiazolecarboxylic acid

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel

Versuchsvorschrift

2-(Pyridin-3-ylamino)-thiazole-4-carboxylic acid (165 mg) was prepared according to General Procedure C using 2-(pyridin-3-ylamino)-thiazole-4-carboxylic acid ethyl ester in methanol:tetrahydrofuran:2N NaOH (1:1:1, 1.5 mL). The solvents were evaporated and the compound was dried. The crude product was used without further purification.

Aufarbeitung

  1. customThe solvents were evaporated
  2. customthe compound was dried
  3. customThe crude product was used without further purification

Quellen und Nachweise

ORD-Eintrag
ord-95270e6983294e26ab93f029557e5b78
Quelldatensatz
uspto-grants-2013_08
Patentnummer
US08513430B2

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