1-Iodopropane → N6-Methyl-N11-propyl-6,11-dihydro-5H-pyrido(2,3-b)(1,5)benzodiazepin-5-one

HRID 1898871

Reaktionsgleichung

Reaktionsgleichung von HRID 1898871
[CH3:1][N:2]1[C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=2[NH:6][C:5]2[N:13]=[CH:14][CH:15]=[CH:16][C:4]=2[C:3]1=[O:17].I[CH2:19][CH2:20][CH3:21]>>[CH3:1][N:2]1[C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=2[N:6]([CH2:19][CH2:20][CH3:21])[C:5]2[N:13]=[CH:14][CH:15]=[CH:16][C:4]=2[C:3]1=[O:17]

Komponenten

3

Edukt 2

HCID 336431-IodopropaneHCID 4532455H-Pyrido(2,3-b)(1,5)benzodiazepin-5-one, 6,11-dihydro-6-methyl-

Produkt 1

HCID 453255N6-Methyl-N11-propyl-6,11-dihydro-5H-pyrido(2,3-b)(1,5)benzodiazepin-5-oneAusbeute 36 %

Versuchsvorschrift

Using a procedure analogous to that described in Example 2, the product 6,11-dihydro-6-methyl-11-propyl-5H-pyrido[2,3-b][1,5]benzodiazepin-5-one, m.p. 96°-98° C. (recrystal from petroleum ether) was prepared from 6,11-dihydro-6-methyl-5H-pyrido[2,3-b][1,5]benzodiazepin-5-one and 1-iodopropane. The yield was 36% of theory.

Quellen und Nachweise

ORD-Eintrag
ord-567270beae7d40ada4675bf13c175bea
Quelldatensatz
uspto-grants-1996_11
Patentnummer
US05571809

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