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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1898938Erstellt: 26. Oktober 2026

Sodium Hydroxide → 1-Isopropyl-2-oxo-1,2-dihydro-3-quinolinecarboxylic acid

https://huagongshe.com/reaction/1898938

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktSodium HydroxideHCID 14798—
EduktEthyl 1-isopropyl-2-oxo-1,2-dihydro-3-quinolinecarboxylateHCID 15468682—
LösungsmittelEthanolHCID 702—
LösungsmittelWaterHCID 962—
Produkt1-Isopropyl-2-oxo-1,2-dihydro-3-quinolinecarboxylic acidHCID 1094429088,3%

Reaktionsschritte

A solution of 1.55 g of ethyl 1-isopropyl-2(1H)-quinolone-3-carboxylate and 0.28 g of sodium hydroxide in a mixture of 10 ml of ethanol and 2 ml of water was stirred overnight at room temperature. After the solvent was distilled off, dil. hydrochloric acid was added to the residue. The precipitated solid was taken by filtration, washed with water and dried to give 1.22 g of 1-isopropyl-2(1H)-quinolone-3-carboxylic acid.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS05571820
Quelldatensatzuspto-grants-1996_11
ORD IDord-517c823989d348d195c3c138d15bd565
Quellennotizuspto-grants-1996_11