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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1899690Erstellt: 25. Oktober 2026

Sulfisoxazole → 1-Cyclohexyl-3-[4-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl]urea

https://huagongshe.com/reaction/1899690

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktSulfisoxazoleHCID 5344—
EduktCyclohexyl isocyanateHCID 18502—
Produkt1-Cyclohexyl-3-[4-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl]ureaHCID 4054520—

Reaktionsschritte

This compound was prepared from 4-amino-N-(3,4-dimethyl-5-isoxazolyl)benzene-sulfonamide and cyclohexyl isocyanate according to the method in Example 110 in 75% crude yield. Further purification was achieved by preparative HPLC (76% recovery), furnishing the pure product as a white solid, m.p. 190°-195° C.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS05571821
Quelldatensatzuspto-grants-1996_11
ORD IDord-038f879dac3c45869fa859d2befa14a5
Quellennotizuspto-grants-1996_11