HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Potassium Carbonate → 8-[2-(2,6-Dichlorophenyl)ethyloxy]-2-methylimidazo[1,2-a]pyridine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Potassium Carbonate | HCID 11430 | — |
| Edukt | 2-Methylimidazo[1,2-a]pyridin-8-ol | HCID 820953 | — |
| Edukt | 2-(2,6-Dichlorophenyl)ethyl methanesulfonate | HCID 15565622 | — |
| Lösungsmittel | Dimethylformamide | HCID 6228 | — |
| Produkt | 8-[2-(2,6-Dichlorophenyl)ethyloxy]-2-methylimidazo[1,2-a]pyridine | HCID 18923336 | 23,4% |
Reaktionsbedingungen
| Temperatur | 70 °C |
|---|
Reaktionsschritte
A mixture of 8-hydroxy-2-methylimidazo[1,2-a]pyridine (296 mg), 1,3-dichloro-2-(2-mesyloxyethyl)benzene (645 mg) and potassium carbonate (828 mg) in N,N-dimethylformamide (12 ml) was stirred for 6 hours at 70° C. The mixture was treated according to a similar manner to that of Preparation 16 to give 8-[2-(2,6-dichlorophenyl)ethyloxy]-2-methylimidazo[1,2-a]pyridine (150 mg).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05574042 |
| Quelldatensatz | uspto-grants-1996_11 |
| ORD ID | ord-79e4e9a227d746999971af3f79d34596 |
| Quellennotiz | uspto-grants-1996_11 |