Methyl 3-aminopropanoate hydrochloride → Methyl 3-((furan-2-ylmethyl)amino)propanoate
Reaktionsgleichung
S1[CH:5]=[CH:4][CH:3]=[C:2]1[CH2:6][NH:7][CH2:8][CH2:9][C:10]([O:12][CH3:13])=[O:11].Cl.NCCC(OC)=[O:19]>>[O:19]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH2:6][NH:7][CH2:8][CH2:9][C:10]([O:12][CH3:13])=[O:11]Komponenten
3
Versuchsvorschrift
Methyl 3-[(2-furanylmethyl)amino]propanoate (22) was prepared in the manner methyl 3-[(2-thienylmethyl)amino]propanoate (15) was prepared, as described above in Example 15, on a 6.5 mmol scale from methyl β-alaninate hydrochloride and furrural to yield 0.28 g (28%) of product.
Aufarbeitung
- customwas prepared
Quellen und Nachweise
- ORD-Eintrag
- ord-aca9a0377d7a4a4ca944a4c9f5aabea5
- Quelldatensatz
- uspto-grants-1996_11
- Patentnummer
- US05576315
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