Phosgene → 3-(3-Phenylpropyl)phenyl isocyanate

HRID 1903653

Reaktionsgleichung

Reaktionsgleichung von HRID 1903653
[C:1]1([CH2:7][CH2:8][CH2:9][C:10]2[CH:11]=[C:12]([CH:14]=[CH:15][CH:16]=2)[NH2:13])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:17](Cl)(Cl)=[O:18]>C1(C)C=CC=CC=1>[C:1]1([CH2:7][CH2:8][CH2:9][C:10]2[CH:11]=[C:12]([N:13]=[C:17]=[O:18])[CH:14]=[CH:15][CH:16]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Komponenten

4

Edukt 2

HCID 6371PhosgeneHCID 4273073-(3-Phenylpropyl)aniline

Produkt 1

HCID 127905743-(3-Phenylpropyl)phenyl isocyanateAusbeute 89 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1140TolueneLösungsmittel2×

Versuchsvorschrift

To a solution of 3-(3-phenylpropyl)aniline (11.6 g) in 100 ml of toluene was dropwise added a solution of phosgene (20 g) in 100 ml of toluene at 10°-20° C. The resultant mixture was gradually heated and, after refluxed for 30 minutes, allowed to cool to room temperature. The solvent was removed under reduced pressure, and the residue was distilled under reduced pressure to give 11.6 g of 3-(3-phenylpropyl)phenyl isocyanate (yield, 89%). B.P. 121°-125° C./0.2 mmHg.

Aufarbeitung

  1. temperatureafter refluxed for 30 minutes
  2. customThe solvent was removed under reduced pressure
  3. distillationthe residue was distilled under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-2b1085577a094030a811874d9fb02bcd
Quelldatensatz
uspto-grants-1984_03
Patentnummer
US04437880

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