Sulfuric Acid → Methyl 4-dimethylaminobenzoate

HRID 1904031

Reaktionsgleichung

Reaktionsgleichung von HRID 1904031
[CH3:1][N:2]([CH3:12])[C:3]1[CH:11]=[CH:10][C:6]([C:7]([OH:9])=[O:8])=[CH:5][CH:4]=1.S(=O)(=O)(O)O.[C:18](=O)(O)[O-].[Na+]>CO>[CH3:18][O:8][C:7](=[O:9])[C:6]1[CH:10]=[CH:11][C:3]([N:2]([CH3:12])[CH3:1])=[CH:4][CH:5]=1

Komponenten

5

Edukt 3

HCID 1118Sulfuric AcidHCID 120924-(Dimethylamino)benzoic acidHCID 516892Sodium Bicarbonate

Produkt 1

HCID 70994Methyl 4-dimethylaminobenzoate

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel

Versuchsvorschrift

23 g of 4-dimethylaminobenzoic acid was dissolved in 200 ml of methanol to which was added 2 ml of concentrated sulfuric acid and the mixture was refluxed with heating for 2 days. After cooling, the reaction mixture was poured into an aqueous solution of sodium bicarbonate and the crystals thus deposited were collected by filtration, washed with water and dried to obtain 24 g of 4-dimethylaminobenzoic acid methyl ester having a melting point of 101° to 102° C.

Aufarbeitung

  1. temperaturethe mixture was refluxed
  2. temperaturewith heating for 2 days
  3. temperatureAfter cooling
  4. filtrationthe crystals thus deposited were collected by filtration
  5. washwashed with water
  6. customdried

Quellen und Nachweise

ORD-Eintrag
ord-05ee31fdce14478aabec7f1a824e6376
Quelldatensatz
uspto-grants-1984_03
Patentnummer
US04439519

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