HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Sulfuric Acid → 4-[N-(4-Chloro-benzyl)-amino]-cyclohexanone
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Sulfuric Acid | HCID 1118 | — |
| Edukt | Sodium Hydroxide | HCID 14798 | — |
| Edukt | Potassium Dichromate | HCID 24502 | — |
| Edukt | 4-(4-Chloro-benzylamino)-cyclohexanol | HCID 13670658 | — |
| Produkt | 4-[N-(4-Chloro-benzyl)-amino]-cyclohexanone | HCID 13670664 | — |
Reaktionsbedingungen
| Temperatur | 50 °C |
|---|
Reaktionsschritte
23.9 g (0.1 Mol) of 4-[N-(4-chlorobenzyl)-amino]-cyclohexanol are suspended in 125 ml of ice water and 32 ml of concentrated sulphuric acid are added. Then 29.4 g (0.1 Mol) of potassium dichromate are added in 2 batches and the mixture is heated for 5 hours at 50° C. It is then cooled, made alkaline with sodium hydroxide solution and extracted with chloroform. After concentration, a yellowish oily liquid is obtained.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04843086 |
| Quelldatensatz | uspto-grants-1989_06 |
| ORD ID | ord-8cb584f7ec3f467483e6eb8542080983 |
| Quellennotiz | uspto-grants-1989_06 |