HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-(o-Tolyl)piperazine Hydrochloride → 2-Carbamoyl-7-{2-hydroxy-3-[4-(2-methylphenyl)piperazinyl]propoxy}benzofuran
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-(o-Tolyl)piperazine Hydrochloride | HCID 12227895 | — |
| Edukt | 2-Carbamoyl-7-(2,3-epoxypropoxy)benzofuran | HCID 13729403 | — |
| Produkt | 2-Carbamoyl-7-{2-hydroxy-3-[4-(2-methylphenyl)piperazinyl]propoxy}benzofuran | HCID 13729385 | — |
Reaktionsschritte
The procedures of Example 10 were repeated except that 1.2 g (0.005 mole) of 2-carbamoyl-7-(2,3-epoxypropoxy)benzofuran and 1.2 g (0.0055 mole) of 1-(2-methylphenyl)piperazine hydrochloride were employed. The obtained concentrated residue was crystallized from ethyl acetate and petroleum ether.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04652566 |
| Quelldatensatz | uspto-grants-1987_03 |
| ORD ID | ord-c920629ff2c34bcbb35aacb3fe1b01e1 |
| Quellennotiz | uspto-grants-1987_03 |