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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1906442Erstellt: 26. Oktober 2026

1-(o-Tolyl)piperazine Hydrochloride → 2-Carbamoyl-7-{2-hydroxy-3-[4-(2-methylphenyl)piperazinyl]propoxy}benzofuran

https://huagongshe.com/reaction/1906442

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt1-(o-Tolyl)piperazine HydrochlorideHCID 12227895—
Edukt2-Carbamoyl-7-(2,3-epoxypropoxy)benzofuranHCID 13729403—
Produkt2-Carbamoyl-7-{2-hydroxy-3-[4-(2-methylphenyl)piperazinyl]propoxy}benzofuranHCID 13729385—

Reaktionsschritte

The procedures of Example 10 were repeated except that 1.2 g (0.005 mole) of 2-carbamoyl-7-(2,3-epoxypropoxy)benzofuran and 1.2 g (0.0055 mole) of 1-(2-methylphenyl)piperazine hydrochloride were employed. The obtained concentrated residue was crystallized from ethyl acetate and petroleum ether.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS04652566
Quelldatensatzuspto-grants-1987_03
ORD IDord-c920629ff2c34bcbb35aacb3fe1b01e1
Quellennotizuspto-grants-1987_03