Tetrahydrofuran → 4-(Pyridin-3-yloxy)phenol

Beteiligte Stoffe

Reaktionsschritte

The product from step 1 (130 mg, 0.469 mmol) was added to a vial containing THF (1 ml), EtOH (2.5 ml), 10% Pd/C (110 mg, 0.0469 mmol), charged with H2 and left to stir under H2 atmosphere overnight. The Pd/C was removed by filtering the reaction mixture through celite. The resulting solution was concentrated to give the title compound (97 mg, 100%).

Herkunft & Nachweise