(S,E)-tert-butyl 4-(4-(methylsulfonyl)-2-aminobut-3-en-1-yl)benzylcarbamate → (S,E)-tert-butyl (5-amino-7-(methylsulfonyl)hept-6-en-1-yl)carbamate

HRID 1912369Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1912369
C([NH:20][C@H:21](/[CH:34]=[CH:35]/[S:36]([CH3:39])(=[O:38])=[O:37])[CH2:22][CH2:23][CH2:24][CH2:25][NH:26][C:27](=[O:33])[O:28][C:29]([CH3:32])([CH3:31])[CH3:30])(C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1.CS(/C=C/[C@@H](N)CC1C=CC(CNC(=O)OC(C)(C)C)=CC=1)(=O)=O>>[NH2:20][C@H:21](/[CH:34]=[CH:35]/[S:36]([CH3:39])(=[O:38])=[O:37])[CH2:22][CH2:23][CH2:24][CH2:25][NH:26][C:27](=[O:33])[O:28][C:29]([CH3:32])([CH3:31])[CH3:30]

Komponenten

3

Edukt 2

HCID 71562244(S,E)-tert-butyl 4-(4-(methylsulfonyl)-2-aminobut-3-en-1-yl)benzylcarbamateHCID 86681599(S,E)-tert-butyl (5-(trityl-amino)-7-(methylsulfonyl)hept-6-en-1-yl)carbamate

Produkt 1

HCID 86681598(S,E)-tert-butyl (5-amino-7-(methylsulfonyl)hept-6-en-1-yl)carbamate

Versuchsvorschrift

This compound was prepared from trityl protected amine 73 in a synthetic procedure similar to that for compound 18. The purity was checked by LC-MS analysis and the amine was subjected to the next step without further purification.

Aufarbeitung

  1. customThis compound was prepared from trityl
  2. customthe amine was subjected to the next step without further purification

Quellen und Nachweise

ORD-Eintrag
ord-f5fe96721dad4745ad55a31604d810b3
Quelldatensatz
uspto-grants-2013_12
Patentnummer
US08609610B2

Notizen zur Reaktion

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