3-Cyclopentylpropionyl chloride → HCID 68750982, Verbindung
Reaktionsgleichung
[C:1]([C:5]1[C:6]([NH2:15])=[N:7][N:8]2[CH:13]=[C:12]([CH3:14])[CH:11]=[N:10][C:9]=12)([CH3:4])([CH3:3])[CH3:2].[CH:16]1([CH2:21][CH2:22][C:23](Cl)=[O:24])[CH2:20][CH2:19][CH2:18][CH2:17]1>>[C:1]([C:5]1[C:6]([NH:15][C:23](=[O:24])[CH2:22][CH2:21][CH:16]2[CH2:20][CH2:19][CH2:18][CH2:17]2)=[N:7][N:8]2[CH:13]=[C:12]([CH3:14])[CH:11]=[N:10][C:9]=12)([CH3:4])([CH3:3])[CH3:2]Komponenten
3
Versuchsvorschrift
The product from Example 178A and 3-cyclopentylpropionyl chloride were processed using the method analogous to that described in Example 105C to afford the title compound. 1H NMR (300 MHz, DMSO-d6) δ ppm 1.04-1.15 (m, 2H), 1.43-1.81 (m, 18H), 2.26-2.30 (m, 5H), 8.38 (d, J=2.0 Hz, 1H), 8.75 (s, 1H), 9.62 (br s, 1H); MS (DCI) m/z 329 (M+H)+.
Quellen und Nachweise
- ORD-Eintrag
- ord-7432cbcb1e3a417faa4cc23fe2926be7
- Quelldatensatz
- uspto-grants-2013_12
- Patentnummer