5-Bromo-1,3-dimethyluracil → 1-Butanol
Reaktionsgleichung
Br[C:2]1[C:3](=[O:11])[N:4]([CH3:10])[C:5](=[O:9])[N:6]([CH3:8])[CH:7]=1.[Cl:12][C:13]1[CH:25]=[CH:24][CH:23]=[CH:22][C:14]=1[O:15][CH:16]1[CH2:21][CH2:20][NH:19][CH2:18][CH2:17]1>>[Cl:12][C:13]1[CH:25]=[CH:24][CH:23]=[CH:22][C:14]=1[O:15][CH:16]1[CH2:21][CH2:20][N:19]([C:2]2[C:3](=[O:11])[N:4]([CH3:10])[C:5](=[O:9])[N:6]([CH3:8])[CH:7]=2)[CH2:18][CH2:17]1.[CH2:14]([OH:15])[CH2:13][CH2:25][CH3:24]Komponenten
4
Versuchsvorschrift
The compound 35 (oil) is prepared from the uracil 1c and from the intermediate 8a according to the synthesis method 1 in n-butanol (yield: 17%).
Quellen und Nachweise
- ORD-Eintrag