HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
L-Malic Acid → Sunitinib Malate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | L-Malic Acid | HCID 222656 | — |
| Edukt | Sunitinib | HCID 5329102 | — |
| Lösungsmittel | Pyridine | HCID 1049 | — |
| Produkt | Sunitinib Malate | HCID 6456015 | — |
Reaktionsschritte
Sunitinib base (600 mg) was dissolved in pyridine (5 ml) at 100° C. and L-malic acid (230 mg) was added to the hot solution. Slight heating provided clear solution. Sunitinib malate was formed overnight at 20° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08618309B2 |
| Quelldatensatz | uspto-grants-2013_12 |
| ORD ID | ord-d5e4d1852a6b449f8fd5222a74ae2d90 |
| Quellennotiz | uspto-grants-2013_12 |