HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
L-Malic Acid → Sunitinib Malate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | L-Malic Acid | HCID 222656 | — |
| Edukt | Sunitinib | HCID 5329102 | — |
| Lösungsmittel | Ethyl Acetate | HCID 8857 | — |
| Produkt | Sunitinib Malate | HCID 6456015 | — |
Reaktionsschritte
To Sunitinib base (300 mg), L-malic acid (101 mg), and AcOEt (10 ml) are added, the mixture is heated to 77 C for 10 min, after precipitation the obtained solid is filtered, dried on air.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08618309B2 |
| Quelldatensatz | uspto-grants-2013_12 |
| ORD ID | ord-05ef6dc551c142de985b740b30c151e9 |
| Quellennotiz | uspto-grants-2013_12 |