4-[1,1,1,3,3,3-hexafluoro-2-(methoxymethyl)oxypropan-2-yl]-2-[(1Z)-1-propenyl]-6-propylphenol → HCID 59234895, Verbindung
Reaktionsgleichung
[F:1][C:2]([F:26])([F:25])[C:3]([C:12]1[CH:17]=[C:16]([CH2:18][CH2:19][CH3:20])[C:15]([OH:21])=[C:14](/[CH:22]=[CH:23]\[CH3:24])[CH:13]=1)([O:8][CH2:9][O:10][CH3:11])[C:4]([F:7])([F:6])[F:5]>[C].[Pd].CO>[CH2:18]([C:16]1[CH:17]=[C:12]([C:3]([O:8][CH2:9][O:10][CH3:11])([C:2]([F:1])([F:25])[F:26])[C:4]([F:5])([F:6])[F:7])[CH:13]=[C:14]([CH2:22][CH2:23][CH3:24])[C:15]=1[OH:21])[CH2:19][CH3:20]Komponenten
4
Versuchsvorschrift
Methanol (30 mL) was added to 4-[1,1,1,3,3,3-hexafluoro-2-(methoxymethyl)oxypropan-2-yl]-2-[(1Z)-1-propenyl]-6-propylphenol (1.29 g, 3.34 mmol). A 10% palladium-carbon catalyst (130 mg) was added to the mixed solution, followed by hydrogenation for 20 hours. The catalyst was separated from the reaction solution by filtration, followed by concentration under reduced pressure to obtain 929 mg of 2,6-dipropyl-4-[1,1,1,3,3,3-hexafluoro-2-(methoxymethyl)oxypropan-2-yl]phenol (yield: 72%) as white crystals.