HCID 57733375, Verbindung → HCID 57733330, Verbindung

HRID 1920750Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1920750
[CH2:1]([O:3][C:4](=[O:16])[CH:5]=[C:6]1[CH2:11][CH2:10][N:9]([C:12]([CH3:15])([CH3:14])[CH3:13])[CH2:8][CH2:7]1)[CH3:2].[H][H]>C(O)C>[CH2:1]([O:3][C:4](=[O:16])[CH2:5][CH:6]1[CH2:7][CH2:8][N:9]([C:12]([CH3:15])([CH3:14])[CH3:13])[CH2:10][CH2:11]1)[CH3:2]

Komponenten

4

Edukt 2

HCID 57733375HCID 57733375, VerbindungHCID 178418361HCID 178418361, Verbindung

Produkt 1

HCID 57733330HCID 57733330, VerbindungAusbeute 78 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

To a solution of (1-tert-butyl-piperidin-4-ylidene)-acetic acid ethyl ester (5.1 g, 22.7 mmol) in ethanol (50 mL) 10% Pd/C (0.6 g) was added and the mixture was stirred under the hydrogen atmosphere (42 psi) at ambient temperature for 14 hours. The catalyst was removed by filtration, and the filtrate was concentrated to give the title (4.03 g, yield 78%), which was used in the next step directly.

Aufarbeitung

  1. customThe catalyst was removed by filtration
  2. concentrationthe filtrate was concentrated
  3. customto give the title (4.03 g, yield 78%), which

Quellen und Nachweise

ORD-Eintrag
ord-3fd4387adce24d1f9ff5c2e7e14fbab6
Quelldatensatz
uspto-grants-2012_05
Patentnummer
US08173639B2

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