Phenylacetyl chloride → N-(5-nitropyridin-2-yl)-2-phenylacetamide

Beteiligte Stoffe

Reaktionsschritte

A solution of 2-amino-5-nitropyridine (4.17 g, 30 mmol) in pyridine (30 mL) is stirred at rt and a solution of phenylacetyl chloride (4.64 g, 30 mmol) in THF (30 mL) is added dropwise. The mixture is stirred for 24 h and then poured into ice-water (250 mL) to afford a brown solid, which is used without further purification.

Herkunft & Nachweise