HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1H-Imidazole, 2-(1-methylethyl)- → {8-Chloro-2-difluoromethoxy-3-[4-(2-isopropylimidazol-1-yl)benzyl]-4-methylquinolin-5-yloxy}acetic acid tert-butyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1H-Imidazole, 2-(1-methylethyl)- | HCID 123457 | — |
| Edukt | {8-Chloro-2-difluoromethoxy-4-methyl-3-[4-(4,4,5,5-tetramethyl[1,3,2]dioxaborolan-2-yl)benzyl]quinolin-5-yloxy}acetic acid tert-butyl ester | HCID 67458465 | — |
| Produkt | {8-Chloro-2-difluoromethoxy-3-[4-(2-isopropylimidazol-1-yl)benzyl]-4-methylquinolin-5-yloxy}acetic acid tert-butyl ester | HCID 67456320 | — |
Reaktionsschritte
The title compound was prepared by the method of Preparation 18a using {8-chloro-2-difluoromethoxy-4-methyl-3-[4-(4,4,5,5-tetramethyl[1,3,2]dioxaborolan-2-yl)benzyl]quinolin-5-yloxy}acetic acid tert-butyl ester and 2-isopropyl-1H-imidazole.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08173812B2 |
| Quelldatensatz | uspto-grants-2012_05 |
| ORD ID | ord-538df5cb5cc4445ba82e4698676b103a |
| Quellennotiz | uspto-grants-2012_05 |