(4-Isopropylphenyl)hydrazine → 3-[2-(4-Isopropyl-phenyl)-2H-pyrazol-3-yl]-1-(3-trifluoromethoxy-phenyl)-1H-pyridazin-4-one
Reaktionsgleichung
C[N:2](C)/[CH:3]=[CH:4]/[C:5]([C:7]1[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]2[CH:19]=[CH:18][CH:17]=[C:16]([O:20][C:21]([F:24])([F:23])[F:22])[CH:15]=2)[N:8]=1)=O.[CH:26]([C:29]1[CH:34]=[CH:33][C:32]([NH:35]N)=[CH:31][CH:30]=1)([CH3:28])[CH3:27]>>[CH:26]([C:29]1[CH:34]=[CH:33][C:32]([N:35]2[C:5]([C:7]3[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]4[CH:19]=[CH:18][CH:17]=[C:16]([O:20][C:21]([F:24])([F:23])[F:22])[CH:15]=4)[N:8]=3)=[CH:4][CH:3]=[N:2]2)=[CH:31][CH:30]=1)([CH3:28])[CH3:27]Komponenten
3
Versuchsvorschrift
Reaction of 3-((E)-3-dimethylamino-acryloyl)-1-(3-trifluoromethoxy-phenyl)-1H-pyridazin-4-one (A-6) and (4-isopropyl-phenyl)-hydrazine according to example 43 gave the desired product. MS: M=441.0 (M+H)+
Quellen und Nachweise
- ORD-Eintrag
- ord-591ce98d5de24b71aba904fd341c83b8
- Quelldatensatz
- uspto-grants-2012_05