4-Amino-3-chlorobenzonitrile → 2-Chloro-1,3-benzothiazole-6-carbonitrile

Reaktionsgleichung

[NH2:1][C:2]1[CH:9]=[CH:8][C:5]([C:6]#[N:7])=[CH:4][C:3]=1Cl.SC1SC2C=C(C#N)C=CC=2N=1.[Cl:23][C:24]1[S:25]C2C=CC(Cl)=CC=2N=1>>[Cl:23][C:24]1[S:25][C:3]2[CH:4]=[C:5]([C:6]#[N:7])[CH:8]=[CH:9][C:2]=2[N:1]=1

Komponenten

Edukt 3

HCID 5198964-Amino-3-chlorobenzonitrile

HCID 133148162,5-Dichloro-1,3-benzothiazole

HCID 1785095042-Sulfanylidene-2,3-dihydro-1,3-benzothiazole-6-carbonitrile

Produkt 1

HCID 219858592-Chloro-1,3-benzothiazole-6-carbonitrile

Reaktionsbedingungen

Temperatur: 120 °C

Versuchsvorschrift

The title compound was prepared from 4-amino-3-chlorobenzonitrile via 2-mercapto-1,3-benzothiazole-6-carbonitrile as described for 2,5-dichloro-1,3-benzothiazole except that in the first step the reaction mixture was heated to 120° C. for 12 h.