2-(2,4-Dimethyl-1H-imidazol-1-yl)ethanamine → 1,3-Dimethyl-8-[2-(4-trifluoromethyl-phenyl)-ethyl]-5,6,7,8-tetrahydro-imidazo[1,5-a]pyrazine
Reaktionsgleichung
[CH3:1][C:2]1[N:3]([CH2:8][CH2:9][NH2:10])[CH:4]=[C:5]([CH3:7])[N:6]=1.[F:11][C:12]([F:24])([F:23])[C:13]1[CH:18]=[CH:17][C:16]([CH2:19][CH2:20][CH:21]=O)=[CH:15][CH:14]=1>>[CH3:7][C:5]1[N:6]=[C:2]([CH3:1])[N:3]2[CH2:8][CH2:9][NH:10][CH:21]([CH2:20][CH2:19][C:16]3[CH:17]=[CH:18][C:13]([C:12]([F:11])([F:23])[F:24])=[CH:14][CH:15]=3)[C:4]=12Komponenten
3
Versuchsvorschrift
Prepared according to the previously described general procedure (GP11) by reaction of 2-(2,4-dimethyl-imidazol-1-yl)-ethylamine with 3-(4-trifluoromethyl-phenyl)-propionaldehyde. LC-MS: tR=0.64 min.; [M+H]+=324 g/mol.
Aufarbeitung
- customPrepared