HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Ethanol → 3-Aminoquinoline
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Ethanol | HCID 702 | — |
| Edukt | Ethyl Acetate | HCID 8857 | — |
| Edukt | Stannous Chloride | HCID 24479 | — |
| Edukt | 3-Nitroquinoline | HCID 25551 | — |
| Katalysator | Iron | HCID 23925 | — |
| Katalysator | Palladium | HCID 23938 | — |
| Katalysator | Zinc | HCID 23994 | — |
| Katalysator | Platinum oxide (PtO) | HCID 82844 | — |
| Lösungsmittel | Acetic Acid | HCID 176 | — |
| Lösungsmittel | Methanol | HCID 887 | — |
| Lösungsmittel | Tetrahydrofuran | HCID 8028 | — |
| Produkt | 3-Aminoquinoline | HCID 11375 | — |
Reaktionsschritte
The 3-nitroquinoline derivative of the formula (c) is then catalytically reduced in an inert solvent such as ethanol, ethyl acetate, methanol or THF, using platinum oxide or palladium/carbon, or reduced by iron or zinc and acetic acid or tin (II) chloride, to give the 3-aminoquinoline derivative of the formula (d).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05693651 |
| Quelldatensatz | uspto-grants-1997_12 |
| ORD ID | ord-8821263ce0054d48b38ee0adbffc7235 |
| Quellennotiz | uspto-grants-1997_12 |