HCID 9798400, Verbindung → HCID 18977165, Verbindung

HRID 1939925Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1939925
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7]([NH:9][CH2:10][CH2:11][CH2:12][CH2:13][C:14]2[CH:19]=[CH:18][C:17]([C:20]3[CH:21]=[CH:22][C:23](=[O:26])[NH:24][N:25]=3)=[CH:16][CH:15]=2)=[O:8])[CH:2]=1.[ClH:27].C(O)C>C(O)C>[ClH:27].[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7]([NH:9][CH2:10][CH2:11][CH2:12][CH2:13][C:14]2[CH:19]=[CH:18][C:17]([C:20]3[CH:21]=[CH:22][C:23](=[O:26])[NH:24][N:25]=3)=[CH:16][CH:15]=2)=[O:8])[CH:2]=1

Komponenten

4

Edukt 2

HCID 9798400HCID 9798400, VerbindungHCID 21887872Ethanol hydrochloride

Produkt 1

HCID 18977165HCID 18977165, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

In hot ethanol (180 ml) was dissolved 8.9 g of 6-[4-(4-(pyridin-3-ylcarbonylamino)butyl)phenyl]pyridazin-3(2H)-one. A 18 % hydrochloric acid-ethanol solution (10 ml) was added to the solution, and the mixture was left to stand at room temperature. Precipitated crystal was collected by filtration and washed with cold ethanol to obtain 9.3 g of 6-[4-(4-(pyridin-3-ylcarbonylamino)butyl)phenyl]pyridazin-3(2H)-one hydrochloride.

Aufarbeitung

  1. waitthe mixture was left
  2. customto stand at room temperature
  3. customPrecipitated crystal
  4. filtrationwas collected by filtration
  5. washwashed with cold ethanol

Quellen und Nachweise

ORD-Eintrag
ord-cc715010b6cf41a98e1adf14ef5c7b73
Quelldatensatz
uspto-grants-1997_12
Patentnummer
US05698554

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