Thionyl Chloride → 2-(4-Methylphenyl)propionyl chloride

Beteiligte Stoffe

Reaktionsbedingungen

Reaktionsschritte

160.65 g (1.35 mol) of thionyl chloride are placed in a 1 liter three-necked flask fitted with a mechanical stirrer and a condenser. 164.2 g (0.9 mol) of p-methylphenylpropionic acid are added little by little thereto at room temperature. After 4 hours, the reaction is terminated by heating at 60° C. for 1 hour. Excess SOCl2 is removed by distillation/n vacuo. In that manner 164.5 g of p-methylphenylpropionic acid chloride are obtained.

Herkunft & Nachweise