Propyl-(4,5,6,7-tetrahydro-benzothiazol-6-yl)-amine → Ethyl-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propyl}-(4,5,6,7-tetrahydro-benzothiazol-6-yl)-amine
Reaktionsgleichung
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[N:9]1[CH2:14][CH2:13][N:12]([CH2:15][CH2:16][CH:17]=O)[CH2:11][CH2:10]1.[CH2:19]([NH:22][CH:23]1[CH2:31][CH2:30][C:26]2[N:27]=[CH:28][S:29][C:25]=2[CH2:24]1)[CH2:20]C>>[CH2:19]([N:22]([CH2:17][CH2:16][CH2:15][N:12]1[CH2:13][CH2:14][N:9]([C:4]2[CH:5]=[CH:6][CH:7]=[CH:8][C:3]=2[O:2][CH3:1])[CH2:10][CH2:11]1)[CH:23]1[CH2:31][CH2:30][C:26]2[N:27]=[CH:28][S:29][C:25]=2[CH2:24]1)[CH3:20]Komponenten
3
Versuchsvorschrift
Compound 29 is prepared from 29B and 1C as described for 1. The salt of maleic acid is crystallized from ethanol/diethylether.
Aufarbeitung
- customThe salt of maleic acid is crystallized from ethanol/diethylether