Boron tribromide → HCID 44610278, Verbindung
Reaktionsgleichung
[Br:1][C:2]1[CH:3]=[C:4]([C:11]([N:13]2[CH2:18][C:17]([CH3:20])([CH3:19])[O:16][C:15]3[CH:21]=[CH:22][N:23]=[CH:24][C:14]2=3)=[O:12])[CH:5]=[C:6]([Br:10])[C:7]=1[O:8]C.B(Br)(Br)Br>>[Br:1][C:2]1[CH:3]=[C:4]([C:11]([N:13]2[CH2:18][C:17]([CH3:19])([CH3:20])[O:16][C:15]3[CH:21]=[CH:22][N:23]=[CH:24][C:14]2=3)=[O:12])[CH:5]=[C:6]([Br:10])[C:7]=1[OH:8]Komponenten
3
Versuchsvorschrift
By the same method as in Example 6, (3,5-dibromo-4-methoxy-phenyl)-(2,2-dimethyl-2,3-dihydro-pyrido[4,3-b][1,4]oxazin-4-yl)-methanone (70 mg, 0.15 mmol) was reacted with 1M solution of boron tribromide (0.9 ml, excess amount) to obtain the target compound 9, (3,5-dibromo-4-hydroxy-phenyl)-(2,2-dimethyl-2,3-dihydro-pyrido[4,3-b][1,4]oxazin-4-yl)-methanone (33 mg, 49%).
Quellen und Nachweise
- ORD-Eintrag
- ord-35338b6114ae44f2bcaccb9324d4d560
- Quelldatensatz
- uspto-grants-2013_03