(3,4-Dichloroisothiazol-5-yl)methanol → 3,4-Dichloro-1,2-thiazole-5-carbaldehyde
Reaktionsgleichung
[Cl:1][C:2]1[C:6]([Cl:7])=[C:5]([CH2:8][OH:9])[S:4][N:3]=1>[O-2].[O-2].[Mn+4].C(Cl)(Cl)Cl>[Cl:1][C:2]1[C:6]([Cl:7])=[C:5]([CH:8]=[O:9])[S:4][N:3]=1Komponenten
4
Edukt 1
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 2
Reaktionsbedingungen
- Temperatur
- 40 °C
Versuchsvorschrift
A mixture of (3,4-dichloroisothiazol-5-yl)methanol (1.1 g), chloroform (150 mL) and manganese dioxide (4.7 g) was stirred at 40° C. for 20 hours. The mixture was filtered through Celite and the filtrate was concentrated under reduced pressure to afford the title compound as a yellow solid (0.62 g).
Aufarbeitung
- filtrationThe mixture was filtered through Celite
- concentrationthe filtrate was concentrated under reduced pressure
Quellen und Nachweise
- ORD-Eintrag
- ord-9d36426fc4e440b4995a198cfe647ddb
- Quelldatensatz
- uspto-grants-2013_03
- Patentnummer
- US08394836B2
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