HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
5-(Bromomethyl)-1,2-oxazole → 4-(8-((1-(isoxazol-5-ylmethyl)azetidin-3-yl)methyl)-9-methyl-2-(2-methyl-1H-benzo[d]imidazol-1-yl)-9H-purin-6-yl)morpholine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 5-(Bromomethyl)-1,2-oxazole | HCID 10034903 | — |
| Edukt | 8-Azetidin-3-ylmethyl-2-(2-methylbenzoimidazol-1-yl)-9-methyl-6-morpholin-4-yl-9H-purine | HCID 59605459 | — |
| Produkt | 4-(8-((1-(isoxazol-5-ylmethyl)azetidin-3-yl)methyl)-9-methyl-2-(2-methyl-1H-benzo[d]imidazol-1-yl)-9H-purin-6-yl)morpholine | HCID 59605780 | — |
Reaktionsschritte
Following General Procedure C, 4-(8-(azetidin-3-ylmethyl)-9-methyl-2-(2-methyl-1H-benzo[d]imidazol-1-yl)-9H-purin-6-yl)morpholine and 5-(bromomethyl)isoxazole were reacted to give 571. LCMS m/z: 250.7 (2M+H+)
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08394796B2 |
| Quelldatensatz | uspto-grants-2013_03 |
| ORD ID | ord-ec5cb61adc6941009026dc15c8881fb9 |
| Quellennotiz | uspto-grants-2013_03 |