N-Isopropylpropylamine → N-1H-indazol-5-yl-6-[isopropyl(propyl)amino]pyrimidine-4-carboxamide

HRID 1946763

Reaktionsgleichung

Reaktionsgleichung von HRID 1946763
Cl[C:2]1[N:7]=[CH:6][N:5]=[C:4]([C:8]([NH:10][C:11]2[CH:12]=[C:13]3[C:17](=[CH:18][CH:19]=2)[NH:16][N:15]=[CH:14]3)=[O:9])[CH:3]=1.[CH2:20]([NH:23][CH:24]([CH3:26])[CH3:25])[CH2:21][CH3:22]>>[NH:16]1[C:17]2[C:13](=[CH:12][C:11]([NH:10][C:8]([C:4]3[CH:3]=[C:2]([N:23]([CH:24]([CH3:26])[CH3:25])[CH2:20][CH2:21][CH3:22])[N:7]=[CH:6][N:5]=3)=[O:9])=[CH:19][CH:18]=2)[CH:14]=[N:15]1

Komponenten

3

Edukt 2

HCID 89119N-IsopropylpropylamineHCID 594468806-chloro-N-1H-indazol-5-ylpyrimidine-4-carboxamide2×

Produkt 1

HCID 25182917N-1H-indazol-5-yl-6-[isopropyl(propyl)amino]pyrimidine-4-carboxamide

Versuchsvorschrift

Following the general method as outlined in Example 20, starting from 6-chloro-pyrimidine-4-carboxylic acid (1H-indazol-5-yl)-amide (Intermediate 16) and propyl-isopropylamine (Matrix), the title compound was obtained as a white solid.

Quellen und Nachweise

ORD-Eintrag
ord-df8567d0899f4486a20bb2c5269c683f
Quelldatensatz
uspto-grants-2013_03
Patentnummer
US08399448B2

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