Trifluoroacetic acid → 7-amino-2-methyl-1-oxo-2,3-dihydro-1H-isoindole-4-carboxylic acid

HRID 1947889Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1947889
C(OC([NH:8][C:9]1[C:17]2[C:16](=[O:18])[N:15]([CH3:19])[CH2:14][C:13]=2[C:12]([C:20]([OH:22])=[O:21])=[CH:11][CH:10]=1)=O)(C)(C)C.C(O)(C(F)(F)F)=O>>[NH2:8][C:9]1[C:17]2[C:16](=[O:18])[N:15]([CH3:19])[CH2:14][C:13]=2[C:12]([C:20]([OH:22])=[O:21])=[CH:11][CH:10]=1

Komponenten

3

Edukt 2

HCID 6422Trifluoroacetic acidHCID 672564057-[(Tert-butoxycarbonyl)amino]-2-methyl-1-oxo-2,3-dihydro-1H-isoindole-4-carboxylic acid

Produkt 1

HCID 672542797-amino-2-methyl-1-oxo-2,3-dihydro-1H-isoindole-4-carboxylic acid

Versuchsvorschrift

The title compound was prepared by deprotecting Compound 116C with TFA. The crude product was taken on to the next step without purification.

Aufarbeitung

  1. customThe crude product was taken on to the next step without purification

Quellen und Nachweise

ORD-Eintrag
ord-b0aba7bb9d2343b3939ab5a3f0f58a1b
Quelldatensatz
uspto-grants-2013_03
Patentnummer
US08399433B2

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