3-Fluoro-5-methoxy-4-nitrobenzonitrile → 2-Fluoro-3-methoxy-4-nitrobenzonitrile
Reaktionsgleichung
F[C:2]1[CH:3]=[C:4]([CH:7]=[C:8]([O:13][CH3:14])[C:9]=1[N+:10]([O-:12])=[O:11])[C:5]#[N:6].BrC1C=CC([N+]([O-])=O)=C(OC)C=1[F:27]>>[F:27][C:7]1[C:8]([O:13][CH3:14])=[C:9]([N+:10]([O-:12])=[O:11])[CH:2]=[CH:3][C:4]=1[C:5]#[N:6]Komponenten
3
Versuchsvorschrift
The title compound was prepared according to the procedure for 3-fluoro-5-methoxy-4-nitrobenzonitrile (Compound 146F) using 1-Bromo-2-fluoro-3-methoxy-4-nitrobenzene (Compound 147G). 1H NMR (CDCl3, 400 MHz): δ=4.15 (d, J=2.27 Hz, 3H), 7.45 (dd, J=8.59, 5.56 Hz, 1H), 7.64 (dd, J=8.59, 1.77 Hz, 1H).
Quellen und Nachweise
- ORD-Eintrag
- ord-ffe9fbd631a84936bcfc6120c7d2f472
- Quelldatensatz
- uspto-grants-2013_03
- Patentnummer
- US08399433B2
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