Aic-292 → HCID 44230249, Verbindung
Reaktionsgleichung
[F:1][C:2]([F:29])([F:28])[C:3]1[CH:4]=[C:5]([C:13]2[N:17]([C:18]3[CH:23]=[CH:22][CH:21]=[C:20]([Cl:24])[CH:19]=3)[N:16]=[C:15]([C:25]([OH:27])=O)[CH:14]=2)[CH:6]=[C:7]([C:9]([F:12])([F:11])[F:10])[CH:8]=1.ClC1C=C(N2C(C3C=C(F)C=C(Cl)C=3)=CC(C([N:53]3[CH2:57][C:56](=[O:58])[NH:55][CH2:54]3)=O)=N2)C=CC=1F>>[F:11][C:9]([F:12])([F:10])[C:7]1[CH:6]=[C:5]([C:13]2[N:17]([C:18]3[CH:23]=[CH:22][CH:21]=[C:20]([Cl:24])[CH:19]=3)[N:16]=[C:15]([C:25]([N:53]3[CH2:57][C:56](=[O:58])[NH:55][CH2:54]3)=[O:27])[CH:14]=2)[CH:4]=[C:3]([C:2]([F:1])([F:28])[F:29])[CH:8]=1Komponenten
3
Versuchsvorschrift
The preparation of the title compound takes place starting from the compound of Example 103A in analogy to the synthesis of the compound of Example 1. 26 mg (72% of theory) of the title compound are obtained.
Quellen und Nachweise
- ORD-Eintrag
- ord-2e95d4dc03de4e4384b03bb356c1604c
- Quelldatensatz
- uspto-grants-2013_03
- Patentnummer
- US08399682B2
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