Sodium Hydroxide → (E)-3-[4-(3-Dimethylaminopropenyl)phenyl]acrylic Acid

HRID 1953521Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1953521
[CH3:1][N:2]([CH3:18])[CH2:3][CH:4]=[CH:5][C:6]1[CH:11]=[CH:10][C:9](/[CH:12]=[CH:13]/[C:14]([O:16]C)=[O:15])=[CH:8][CH:7]=1.[OH-].[Na+]>CO>[CH3:18][N:2]([CH3:1])[CH2:3][CH:4]=[CH:5][C:6]1[CH:11]=[CH:10][C:9](/[CH:12]=[CH:13]/[C:14]([OH:16])=[O:15])=[CH:8][CH:7]=1

Komponenten

4

Edukt 2

HCID 14798Sodium HydroxideHCID 86755260(E)-3-[4-(3-dimethylaminopropenyl)phenyl]acrylic acid, methyl ester

Produkt 1

HCID 70098974(E)-3-[4-(3-Dimethylaminopropenyl)phenyl]acrylic AcidAusbeute 85 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel

Versuchsvorschrift

This product was prepared by refluxing for four hours, (E)-3-[4-(3-dimethylaminopropenyl)phenyl]acrylic acid, methyl ester with NaOH (0.16 g, 2 equiv.) in 10 mL of MeOH. After evaporation of the solvent in vacuo, treatment with 5 mL of HCl (1N) gave the title compound (0.4 g, 85%) as a gummy orange solid.

Aufarbeitung

  1. customThis product was prepared
  2. temperatureby refluxing for four hours
  3. customAfter evaporation of the solvent in vacuo, treatment with 5 mL of HCl (1N)

Quellen und Nachweise

ORD-Eintrag
ord-4732a76e30ec461c99139977ab9ac3cd
Quelldatensatz
uspto-grants-2000_09
Patentnummer
US06117881

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