(E)-2-(4,6-difluoro-1-indanylidene)acetic acid → (E)-2-(5-fluoro-1-indanylidene)acetyl Chloride

HRID 1954880Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1954880
F[C:2]1[CH:10]=[C:9](F)[CH:8]=[C:7]2[C:3]=1[CH2:4][CH2:5]/[C:6]/2=[CH:12]\[C:13]([Cl:15])=[O:14].[F:16]C1C=C(F)C=C2C=1CC/C/2=C\C(O)=O>>[F:16][C:10]1[CH:2]=[C:3]2[C:7](=[CH:8][CH:9]=1)/[C:6](=[CH:12]/[C:13]([Cl:15])=[O:14])/[CH2:5][CH2:4]2

Komponenten

3

Edukt 2

HCID 10976722(E)-2-(4,6-difluoro-1-indanylidene)acetic acidHCID 10977254(E)-2-(4,6-difluoro-1-indanylidene)acetyl Chloride

Produkt 1

HCID 23293623(E)-2-(5-fluoro-1-indanylidene)acetyl Chloride

Versuchsvorschrift

This compound was prepared in a similar manner to (E)-2-(4,6-difluoro-1-indanylidene)acetyl chloride in Example 5f by substituting (E)-2-(5-fluoro-1-indanylidene)acetic acid (5.77 g, 0.03 mol) for (E)-2-(4,6-difluoro-1-indanylidene)acetic acid. The resulting solution was concentrated in vacuo, and the residue was used without further purification.

Aufarbeitung

  1. concentrationThe resulting solution was concentrated in vacuo
  2. customthe residue was used without further purification

Quellen und Nachweise

ORD-Eintrag
ord-8fcf4761d31f46b2b202001c3df4c7c2
Quelldatensatz
uspto-grants-2000_09
Patentnummer
US06124284

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