Acetyl chloride → HCID 54052838, Verbindung

HRID 1957357Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1957357
[C:1](Cl)(=[O:3])[CH3:2].[N:5]1[CH:10]=[CH:9][CH:8]=[C:7]([CH:11]=[N:12][N:13]2[CH:17]=[N:16][NH:15][C:14]2=[O:18])[CH:6]=1>N1C=CC=CC=1>[C:1]([N:15]1[C:14](=[O:18])[N:13]([N:12]=[CH:11][C:7]2[CH:6]=[N:5][CH:10]=[CH:9][CH:8]=2)[CH:17]=[N:16]1)(=[O:3])[CH3:2]

Komponenten

4

Edukt 2

HCID 6367Acetyl chlorideHCID 54560653HCID 54560653, Verbindung

Produkt 1

HCID 54052838HCID 54052838, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1049PyridineLösungsmittel

Versuchsvorschrift

2.4 g of acetyl chloride are added to a suspension of 3.8 g of 4-(pyridin-3-ylmethyleneamino)-1,2,4-triazol-3-one in 50 ml of pyridine. The resulting solution is stirred for 14 hours at 20° and then concentrated by evaporation. Water is added to the residue and extraction is carried out with chloroform. The organic phase is concentrated by evaporation and the residue is stirred with ether. The crystals are filtered off with suction and then dried under a high vacuum. 4 g of the title compound having a melting point of 164°-166° are thus obtained.

Aufarbeitung

  1. concentrationconcentrated by evaporation
  2. additionWater is added to the residue and extraction
  3. concentrationThe organic phase is concentrated by evaporation
  4. stirringthe residue is stirred with ether
  5. filtrationThe crystals are filtered off with suction
  6. customdried under a high vacuum
  7. customare thus obtained

Quellen und Nachweise

ORD-Eintrag
ord-db68af07607d440ca2577aecf2344f77
Quelldatensatz
uspto-grants-1998_07
Patentnummer
US05783704

Notizen zur Reaktion

Wird geladen…