Allyl bromide → 4-Allyloxy-2,5-dichloronitrobenzene

HRID 1957471

Reaktionsgleichung

Reaktionsgleichung von HRID 1957471
[Cl:1][C:2]1[CH:7]=[C:6]([N+:8]([O-:10])=[O:9])[C:5]([Cl:11])=[CH:4][C:3]=1[OH:12].C(=O)([O-])[O-].[K+].[K+].[CH2:19](Br)[CH:20]=[CH2:21]>C(#N)C>[CH2:21]([O:12][C:3]1[C:2]([Cl:1])=[CH:7][C:6]([N+:8]([O-:10])=[O:9])=[C:5]([Cl:11])[CH:4]=1)[CH:20]=[CH2:19]

Komponenten

5

Edukt 3

HCID 7841Allyl bromideHCID 11430Potassium CarbonateHCID 221082,5-Dichloro-4-nitrophenol

Produkt 1

HCID 190676764-Allyloxy-2,5-dichloronitrobenzeneAusbeute 93,5 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6342AcetonitrileLösungsmittel

Versuchsvorschrift

The product of step (a) (59.3 g, 285 mmol), 550 ml acetonitrile, 43 g (314 mmol) of potassium carbonate and 27.2 ml (314 mmol) of allyl bromide were combined and heated to reflux, and then the reaction was evaporated under reduced pressure. The mixture was extracted with diethyl ether, washed with water, and separated. The organics were dried over magnesium sulfate and stripped to yield 66.1 g of 4-allyloxy-2,5-dichloronitrobenzene product.

Aufarbeitung

  1. temperatureheated
  2. temperatureto reflux
  3. customthe reaction was evaporated under reduced pressure
  4. extractionThe mixture was extracted with diethyl ether
  5. washwashed with water
  6. customseparated
  7. dry with materialThe organics were dried over magnesium sulfate

Quellen und Nachweise

ORD-Eintrag
ord-b1d3a2b801a248e68ada93e3f0958bd5
Quelldatensatz
uspto-grants-1998_07
Patentnummer
US05786301

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