Acetonitrile → HCID 178507819, Verbindung

HRID 1957518Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1957518
[NH2:1][C:2]1[C:7]2[O:8][CH2:9][CH2:10][O:11][C:6]=2[C:5](C(O)=O)=[CH:4][C:3]=1[Cl:15].[C:16](#[N:18])[CH3:17]>>[NH2:1][C:2]1[C:7]2[O:8][CH2:9][CH2:10][O:11][C:6]=2[CH:5]=[CH:4][C:3]=1[Cl:15].[NH:18]1[C-:16]=[CH:17][N:1]=[CH:2]1

Komponenten

3

Edukt 2

HCID 6342AcetonitrileHCID 117759978-Amino-7-chloro-2,3-dihydro-1,4-benzodioxine-5-carboxylic acid

Produkt 1

HCID 178507819HCID 178507819, Verbindung

Versuchsvorschrift

To a stirred solution of 8-amino-7-chloro-1,4-benzodioxan-5-carboxylic acid (prepared from the corresponding 7-H acid (prepared as in GB 1571278) by chlorination of the protected form) (1.10 g) in acetonitrile was added biscarbonyldiimidazole (0.77 g). The reaction mixture was stirred at room temperature for 1.5 hours. The solvent was removed under reduced pressure to afford crude 8-amino-7-chloro-1,4-benzodioxan-5-imidazolide.

Aufarbeitung

  1. customThe solvent was removed under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-41361a8672a44e33b8496e820a715ce8
Quelldatensatz
uspto-grants-1998_07
Patentnummer
US05786372

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