2-chloro-8-isopropyl-5-methyl-7,8-dihydro-5H-pteridin-6-one → HCID 68422327, Verbindung
Reaktionsgleichung
Cl[C:2]1[N:11]=[CH:10][C:9]2[N:8]([CH3:12])[C:7](=[O:13])[CH2:6][N:5]([CH:14]([CH3:16])[CH3:15])[C:4]=2[N:3]=1.[CH3:17][S:18]([C:21]1[CH:22]=[C:23]([NH2:30])[CH:24]=[C:25]([N+:27]([O-:29])=[O:28])[CH:26]=1)(=[O:20])=[O:19]>>[CH:14]([N:5]1[C:4]2[N:3]=[C:2]([NH:30][C:23]3[CH:24]=[C:25]([N+:27]([O-:29])=[O:28])[CH:26]=[C:21]([S:18]([CH3:17])(=[O:20])=[O:19])[CH:22]=3)[N:11]=[CH:10][C:9]=2[N:8]([CH3:12])[C:7](=[O:13])[CH2:6]1)([CH3:16])[CH3:15]Komponenten
3
Versuchsvorschrift
Starting from 2-chloro-8-isopropyl-5-methyl-7,8-dihydro-5H-pteridin-6-one (9.35 g; 38.85 mmol) and 3-methansulfonyl-5-nitro-phenylamine (8.4 g; 38.5 mmol), 9.4 g (22.38 mmol; 57.5% yield) of the desired nitro-product were obtained as a powder.
Quellen und Nachweise
- ORD-Eintrag
- ord-979050b490d448e4ad5508f08ab8bb99
- Quelldatensatz
- uspto-grants-2013_04