4-Methyl-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine-7-carboxylic acid → HCID 56962052, Verbindung

HRID 1958199Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1958199
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:9]=[C:10]([NH2:20])[CH:11]=[N:12][C:13]=2[O:14][CH2:15][C:16]([F:19])([F:18])[F:17])=[CH:4][C:3]=1[F:21].[CH3:22][N:23]1[CH2:28][CH2:27][O:26][C:25]2[CH:29]=[C:30]([C:33](O)=[O:34])[CH:31]=[N:32][C:24]1=2>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:9]=[C:10]([NH:20][C:33]([C:30]3[CH:31]=[N:32][C:24]4[N:23]([CH3:22])[CH2:28][CH2:27][O:26][C:25]=4[CH:29]=3)=[O:34])[CH:11]=[N:12][C:13]=2[O:14][CH2:15][C:16]([F:17])([F:18])[F:19])=[CH:4][C:3]=1[F:21]

Komponenten

3

Edukt 2

HCID 242296454-Methyl-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine-7-carboxylic acidHCID 672803905-(4-Chloro-3-fluoro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-ylamine

Produkt 1

HCID 56962052HCID 56962052, Verbindung

Versuchsvorschrift

The title compound was synthesized in analogy to Example 42 g, using 5-(4-chloro-3-fluoro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-ylamine (example 81 a) and 3,4-dihydro-4-methyl-2H-pyrido[3,2-b]-1,4-oxazine-7-carboxylic acid (CAN 915707-58-3) as starting materials; MS (EI) 497.2(M+H)+.

Quellen und Nachweise

ORD-Eintrag
ord-42ca59d0a2714b33bcc97d91d789f1bc
Quelldatensatz
uspto-grants-2013_04
Patentnummer
US08410107B2

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