HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
(Oxiran-2-yl)methyl 3-nitrobenzene-1-sulfonate → (+/-)-1-(Cyclohexylmethyl)-4-(oxiran-2-ylmethyl)piperazine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | (Oxiran-2-yl)methyl 3-nitrobenzene-1-sulfonate | HCID 286836 | — |
| Edukt | 1-(Cyclohexylmethyl)piperazine | HCID 2735885 | — |
| Produkt | (+/-)-1-(Cyclohexylmethyl)-4-(oxiran-2-ylmethyl)piperazine | HCID 86661984 | 92% |
Reaktionsschritte
The same method as employed in the preparation of Intermediate 1 but starting from 1-cyclohexylmethyl piperazine and (±)-3-nitro-benzenesulfonic acid oxiranylmethyl ester gives after flash chromatography the title compound as a yellow oil in a 92% yield.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08410110B2 |
| Quelldatensatz | uspto-grants-2013_04 |
| ORD ID | ord-2536eeedebbf49a0b6412589d7783b57 |
| Quellennotiz | uspto-grants-2013_04 |